Heart - Atirial Fibrillation
What medication for atrial fibrillation? [TranslationAL]
What is the optimal antithrombotic regime for non-valvular atrial fibrillation?

The answer depends on the relative weight attached to avoiding stroke on the one hand and the bleeding associated with the treatments on the other - as well as on the performance of the drugs on these two criteria.

Stephen LaHaye and colleagues developed a clinical decision aid for this question*. Here we reframe it to permit the effect of varying the weighting of avoiding stroke and bleeding to be explored dynamically. We drop their cost attrbute. Guidelines are not considered relevant to this analysis and reimbursability considerations are ignored.

Click next to consult the TranslationAL.

*LaHaye, S. A., Gibbens, S. L., Ball, D. G. A., Day, A. G., Olesen, J. B., & Skanes, A. C. (2012). A clinical decision aid for the selection of antithrombotic therapy for the prevention of stroke due to atrial fibrillation. European heart journal, 33(17), 2163-71. doi:10.1093/eurheartj/ehs167